Get answers to treatment questions
Here’s what to know before you take MAVYRET.
A healthy liver is very important for your overall health. Your liver performs many functions including removing toxins and gathering nutrients from food. Hep C is a viral infection that affects the liver. Over time, a hep C infection may lead to liver damage, such as fibrosis and cirrhosis.
A chronic hep C infection inflames the liver, which can lead to a kind of scarring called fibrosis. Healthcare professionals do a test to learn the level of fibrosis and give an “F-score” to the liver, from F0-F4.
Slide to the right to see how the liver progresses through stages of cirrhosis.
F0
No fibrosis
No liver damage yet
F1
Mild fibrosis
Liver damage is just starting
F2
Moderate fibrosis
Scar tissue is beginning to form
F3
Severe fibrosis
Scar tissue is so bad that it’s affecting blood flow in the liver
F4
Cirrhosis
The liver is taken over by scar tissue and can’t do its job
USE
MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds (45 kilograms) with chronic (lasting a long time) hepatitis C virus (hep C):
IMPORTANT SAFETY INFORMATION ABOUT MAVYRET® (glecaprevir/pibrentasvir)
What is the most important information I should know about MAVYRET?
Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C with MAVYRET. Hep B that becomes active again (called reactivation) may cause serious liver problems, including liver failure and death. Your doctor will monitor you if you are at risk for hep B reactivation during treatment and after you stop taking MAVYRET.
Do not take MAVYRET if you:
What should I tell my doctor before taking MAVYRET?
What are the possible side effects of MAVYRET?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit
or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.