HERE'S HOW HEP C INFECTS THE LIVER

AUDIO: This is your liver, and this is why it’s important.

TEXT ON-SCREEN: YOUR LIVER IS IMPORTANT

AUDIO: Your liver performs many functions…

TEXT ON-SCREEN: YOUR LIVER PERFORMS MANY FUNCTIONS

AUDIO: …including soaking up nutrients from food…

TEXT ON-SCREEN: IT SOAKS UP THE NUTRIENTS FROM FOOD

AUDIO: …and taking toxins out of your blood.

TEXT ON-SCREEN: IT TAKES TOXINS OUT OF YOUR BLOOD

AUDIO: Hep C is a viral infection that affects the liver.

TEXT ON-SCREEN: HEP C IS A VIRAL INFECTION THAT AFFECTS THE LIVER

AUDIO: It can be acute or chronic.

TEXT ON-SCREEN: HEP C CAN BE ACUTE (RECENTLY INFECTED) OR CHRONIC (LASTING A LONG TIME)

AUDIO: Hep C can be asymptomatic. Which means you may not know you have hep C.

TEXT ON-SCREEN: YOU MAY NOT KNOW YOU HAVE HEP C

AUDIO: But even without symptoms…

TEXT ON-SCREEN: EVEN WITHOUT SYMPTOMS

AUDIO: …once the virus gets started…

AUDIO: …hep C never sleeps.

TEXT ON-SCREEN: HEP C NEVER SLEEPS

AUDIO: Hep C affects the liver…

AUDIO: …by multiplying a trillion times in the liver each day.

TEXT ON-SCREEN: IT MULTIPLIES A TRILLION TIMES EACH DAY

AUDIO: MAVYRET directly targets the virus to…

TEXT ON-SCREEN: MAVYRET DIRECTLY TARGETS THE VIRUS

TEXT ON-SCREEN: FOR HEPATITIS (HEP C) GENOTYPES 1-6. SEE SAFETY CONSIDERATIONS AT THE END OF THE VIDEO.

AUDIO: …block the copying process.

TEXT ON-SCREEN: MAVYRET BLOCKS HEP C’S COPYING PROCESS

TEXT ON-SCREEN: FOR HEPATITIS (HEP C) GENOTYPES 1-6. SEE SAFETY CONSIDERATIONS AT THE END OF THE VIDEO.

AUDIO: And MAVYRET can cure those new to treatment in only 8 weeks.

TEXT ON-SCREEN: AND MAVYRET CAN CURE* ALL TYPES OF HEP C IN ONLY 8 WEEKS. FOR THOSE NEW TO TREATMENT.

TEXT ON-SCREEN: *CURE MEANS NO HEP C VIRUS FOUND IN THE BLOOD 3 MONTHS AFTER TREATMENT ENDS. INDIVIDUAL RESULTS MAY VARY.

AUDIO: That’s 4 fewer weeks than most hep C treatments.

TEXT ON-SCREEN: THAT’S 4 FEWER WEEKS THAN MOST HEP C TREATMENTS

TEXT ON-SCREEN: *CURE MEANS NO HEP C VIRUS FOUND IN THE BLOOD 3 MONTHS AFTER TREATMENT ENDS. INDIVIDUAL RESULTS MAY VARY.

AUDIO: So you can put hep C behind you.

TEXT ON-SCREEN: SO YOU CAN PUT HEP C BEHIND YOU

AUDIO: Talk to your doctor to see if MAVYRET is right for you. See full Prescribing Information on the website.

TEXT ON-SCREEN: Talk to your doctor to see if MAVYRET is right for you. See full Prescribing Information on the website.

USE

MAVYRET is a prescription medicine used to treat adults and children 3 years of age and older with:

  • Acute (recently infected) or chronic (lasting a long time) hepatitis C virus (hep C) genotypes 1, 2, 3, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis.
  • Hep C genotype 1 infection who have been previously treated with a regimen that contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not both.

SAFETY CONSIDERATIONS

  • Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C with MAVYRET. Hep B that becomes active again (called reactivation) may cause serious liver problems, including liver failure and death. Your doctor will monitor you if you are at risk for hep B reactivation during treatment and after you stop taking MAVYRET.
  • Do not take MAVYRET if you have moderate or severe liver impairment (Child-Pugh B or C) or any history of prior liver decompensation or if you are taking the medicines atazanavir or rifampin.
  • In people who had or have advanced liver problems before starting treatment with MAVYRET, there is a rare risk of worsening liver problems, liver failure, and death. Your doctor will check you for signs and symptoms of worsening liver problems during treatment with MAVYRET. Tell your doctor right away if you have any of the following: nausea; tiredness; yellowing of your skin or white part of your eyes; bleeding or bruising more easily than normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea; dark or brown (tea-colored) urine; swelling or pain on the upper right side of your stomach area (abdomen); sleepiness; vomiting of blood; or lightheadedness.
  • There are some medicines that you should not take with MAVYRET. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. MAVYRET and other medicines may affect each other. This can cause you to have too much or not enough MAVYRET or other medicines in your body. This may affect the way MAVYRET or your other medicines work or may cause side effects. Do not start a new medicine without telling your doctor.

Please see full Prescribing Information, including the Patient Information, on MAVYRET.com.