Rick Video – Transcript

TEXT ON-SCREEN:

MAVYRET is a prescription medicine used to treat adults with hep C genotypes 1–6.

TEXT ON-SCREEN:

RICK’S PATH TO A HEP C CURE* WITH MAVYRET

*Cure means no virus found in the blood 3 months after treatment ends. Individual results may vary.

Rick:

When the doctor told me I had hepatitis C, I was devastated. My name’s Richard. I go by Rick. I live in Michigan. I work for an automotive company as an engineer. After the Army, I came out and I met my wife...and we had three kids...beautiful kids sometimes, sometimes not so much.

My wife wanted to get the family the hepatitis vaccines for A and B, and that’s when I found out I had hepatitis C. It really put a toll on our family.

TEXT ON-SCREEN:

RICK AND HIS DOCTOR DISCUSS HIS 8-WEEK TREATMENT

Rick:

My wife found out about MAVYRET, so we talked to our doctor and got treatment, and he told me it was three pills a day once a day for eight weeks, I thought, I can try that. It was easy. It was—get up in the morning, take my three pills.

TEXT ON-SCREEN:

8-week treatment for those not previously treated, without cirrhosis, and no history of liver or kidney transplant.

TEXT ON-SCREEN:

3 MONTHS AFTER TREATMENT ENDS...THE CALL RICK DREAMED OF

Rick:

The day that we went to the doctor’s office and they told me I was officially cured, we were so happy. It’s like a burden just lifted from you.

TEXT ON-SCREEN:

Cure means no virus found in the blood 3 months after treatment ends. Individual results may vary.

Rick:

We got to go home and call our children. We told the family and everybody was thrilled...I was officially cured.

TEXT ON-SCREEN:

Visit MAVYRET.com or call 1-877-628-9738

Audio:

Before starting MAVYRET, your doctor will test if you’ve had hepatitis B, which may flare up and cause serious liver problems during and after treatment.

TEXT ON-SCREEN:

If you have ever had hepatitis B it may flare up and cause serious liver problems.

Audio:

Tell your doctor if you’ve had hepatitis B, a liver or kidney transplant, other liver problems, HIV-1, or other medical conditions, and all medicines you take, including herbal supplements.

TEXT ON-SCREEN:

Don’t take MAVYRET with atazanavir or rifampin, or if you’ve had certain liver problems.

Audio:

Don’t take MAVYRET with atazanavir or rifampin, or if you’ve had certain liver problems. Common side effects include headache and tiredness.

TEXT ON-SCREEN:

WHY WAIT? YOUR HEP C COULD BE CURED IN 8 WEEKS

8-week treatment for those not previously treated, without cirrhosis, and no history of liver or kidney transplant.

Rick:

I would say you gotta do it. There’s no reason not to. I mean, you do not have to live with this.

TEXT ON-SCREEN:

Please view full Prescribing Information, including Patient Information, on MAVYRET.com.

TEXT ON-SCREEN:

Individual results may vary.

TEXT ON-SCREEN:

THE 8-WEEK CURE* FOR HEP C

Talk to your doctor to see if MAVYRET is right for you.

*Cure means no virus found in the blood 3 months after treatment ends. Individual results may vary.

USE

MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds (45 kilograms) with:

  • chronic (lasting a long time) hepatitis C virus (hep C) genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis.
  • GT 1 infection and have been previously treated with a regimen that contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not both.

IMPORTANT SAFETY INFORMATION ABOUT MAVYRET® (GLECAPREVIR/PIBRENTASVIR)

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C with MAVYRET. Hep B that becomes active again (called reactivation) may cause serious liver problems, including liver failure and death. Your doctor will monitor you if you are at risk for hep B reactivation during treatment and after you stop taking MAVYRET.

Do not take MAVYRET if you:

  • Have certain liver problems
  • Are taking the medicines atazanavir or rifampin

What should I tell my doctor before taking MAVYRET?

  • If you have had hep B infection, have liver problems other than hep C infection, have HIV-1 infection, have had a liver or a kidney transplant, and all other medical conditions.
  • If you are pregnant or plan to become pregnant, or if you are breastfeeding or plan to breastfeed. It is not known if MAVYRET will harm your unborn baby or pass into your breast milk. Talk to your doctor about the best way to feed your baby if you take MAVYRET.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. MAVYRET and other medicines may affect each other. This can cause you to have too much or not enough MAVYRET or other medicines in your body. This may affect the way MAVYRET or your other medicines work or may cause side effects.
  • Do not start taking a new medicine without telling your doctor. Your doctor can tell you if it is safe to take MAVYRET with other medicines.

What are the possible side effects of MAVYRET?

  • In people who had or have advanced liver problems before starting treatment with MAVYRET, there is a rare risk of worsening liver problems, liver failure, and death. Your doctor will check you for signs and symptoms of worsening liver problems during treatment with MAVYRET. Tell your doctor right away if you have any of the following: nausea; tiredness; yellowing of your skin or white part of your eyes; bleeding or bruising more easily than normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea; dark or brown (tea-colored) urine; swelling or pain on the upper right side of your stomach area (abdomen); sleepiness; vomiting of blood; or lightheadedness.
  • The most common side effects of MAVYRET are headache and tiredness.
These are not all the possible side effects of MAVYRET. Call your doctor for medical advice about side effects.
This is the most important information to know about MAVYRET. For more information, talk to your doctor or healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit

 or call 1-800-FDA-1088.

Please see full Prescribing Information, including the Patient Information.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.

USE

MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds (45 kilograms) with:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do

USE

MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds (45 kilograms) with:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C with MAVYRET. Hep B that becomes active again (called reactivation) may cause serious liver

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do

USE

MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds (45 kilograms) with:

  • chronic (lasting a long time) hepatitis C virus (hep C) genotypes (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis.
  • GT 1 infection and have been previously treated with a regimen that contained a hep C NS5A inhibitor or an NS3/4A protease inhibitor, but not both.

IMPORTANT SAFETY INFORMATION ABOUT MAVYRET® (GLECAPREVIR/PIBRENTASVIR)

What is the most important information I should know about MAVYRET?

Hepatitis B virus (hep B) reactivation: Before starting treatment with MAVYRET, your doctor will do blood tests to check for hep B infection. If you have ever had hep B infection, hep B could become active again during or after treatment for hep C with MAVYRET. Hep B that becomes active again (called reactivation) may cause serious liver problems, including liver failure and death. Your doctor will monitor you if you are at risk for hep B reactivation during treatment and after you stop taking MAVYRET.

Do not take MAVYRET if you:

  • Have certain liver problems
  • Are taking the medicines atazanavir or rifampin

What should I tell my doctor before taking MAVYRET?

  • If you have had hep B infection, have liver problems other than hep C infection, have HIV-1 infection, have had a liver or a kidney transplant, and all other medical conditions.
  • If you are pregnant or plan to become pregnant, or if you are breastfeeding or plan to breastfeed. It is not known if MAVYRET will harm your unborn baby or pass into your breast milk. Talk to your doctor about the best way to feed your baby if you take MAVYRET.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. MAVYRET and other medicines may affect each other. This can cause you to have too much or not enough MAVYRET or other medicines in your body. This may affect the way MAVYRET or your other medicines work or may cause side effects.
  • Do not start taking a new medicine without telling your doctor. Your doctor can tell you if it is safe to take MAVYRET with other medicines.

What are the possible side effects of MAVYRET?

  • In people who had or have advanced liver problems before starting treatment with MAVYRET, there is a rare risk of worsening liver problems, liver failure, and death. Your doctor will check you for signs and symptoms of worsening liver problems during treatment with MAVYRET. Tell your doctor right away if you have any of the following: nausea; tiredness; yellowing of your skin or white part of your eyes; bleeding or bruising more easily than normal; confusion; dark, black, or bloody stool; loss of appetite; diarrhea; dark or brown (tea-colored) urine; swelling or pain on the upper right side of your stomach area (abdomen); sleepiness; vomiting of blood; or lightheadedness.
  • The most common side effects of MAVYRET are headache and tiredness.
These are not all the possible side effects of MAVYRET. Call your doctor for medical advice about side effects.
This is the most important information to know about MAVYRET. For more information, talk to your doctor or healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit

 or call 1-800-FDA-1088.

Please see full Prescribing Information, including the Patient Information.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.